Anyway, I thought it would be cool to post some of the images from my literature talk last week. It was a very cool talk - I got to discuss the role of two protein in 50% of human cancers. Amazing that in a lot of cancer cells, the crazy growth associated with cancer comes from the binding of two proteins. A simple binding event. Of course, other things go wrong in cancer, but a simple binding event can swing the pendulum towards cancer or non-cancer. Blows my mind really!
Anyway, here's a cool image of the two proteins I gave a talk about (my whole talk had pictures like this...). The p53 tumor suppressor is in pink, and the Mdm2 oncogene is in green:

And now for a slightly more Freudian look at a binding site (no I didn't say that in my talk, but I was sorely tempted!). This is a cut into the binding sites of the two proteins:

Pictures made using Pymol, pdb code 1YCR.pdb
1 comment:
I must admit that I greatly enjoyed the preview of your talk that you gave starting 5am on 24 Jan, for about 5 miles along the Capital Crescent Trail, CM! (^_^) --- ^z
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